姓名：周晓波     

职称：讲师（校聘副教授）

个人简介

性别：男   籍贯：安徽

2008.09-2012.06，阜阳师范学院，化学专业，获理学学士学位；

2012.09-2015.06，南京邮电大学，光学工程专业，获工学硕士学位（导师：赵强 教授），

2015.09-2019.06，复旦大学，无机化学专业，或理学博士学位（导师：李富友 教授）；

2019.07-至今，澳网官方网站，澳网官方网站医学检验系，专任教师。

专业研究领域

发光材料的设计、合成及其生物医学应用。研究兴趣主要集中于通过新材料和新方法的开发，提高基于荧光检测原理的疾病诊断技术的灵敏度和准确性

学术论文（选填）

(1) Xiaobo Zhou*^#, Lingfeng Zhao^#, Ke Zhang, Chaojie Yang, Shijie Li, Xiaoxia Kang, Guo Li, Qi Wang, Haiwei Ji, Mingmin Wu, Jinxia Liu, Yuling Qin* and Li Wu*, Ultrabright AIEdots with tunable narrow emission for multiplexed fluorescence imaging[J]. Chem. Sci., 2023, 14, 113-120. IF: 9.969, SCI一区

(2) Xiaobo Zhou, Ke Zhang, Chaojie Yang, Yuetian Pei, Lingfeng Zhao, Xiaoxia Kang, Zhenhua Li, Fuyou Li*, Yuling Qin*, Li Wu*, Ultrabright and highly polarity-sensitive NIR-I/NIR-II fluorophores for the tracking of lipid droplets and staging of fatty liver disease[J]. Adv. Funct. Mater. 2022, 32, 2109929. IF: 19.924, SCI一区

(3) Xiaobo Zhou^#, Qiyu Liu^#, Wei Yuan, Zhenhua Li, Yuliang Xu, Wei Feng, Congjian Xu*, Fuyou Li*, Ultrabright NIR-II emissive polymer dots for metastatic ovarian cancer detection[J], Adv. Sci. 2021, 8(4): 2000441. IF: 17.521, SCI一区

(4) Xiaobo Zhou, Yawei Liu, Qiyu Liu, Luzhe Yan, Meng Xue, Wei Yuan, Mei Shi, Wei Feng, Congjian Xu*, Fuyou Li*, Point-of-care ratiometric fluorescence imaging of tissue for the diagnosis of ovarian cancer[J]. Theranostics 2019, 9(16): 4597-4607. IF: 11.6, SCI一区

(5) Xiaobo Zhou, Hua Liang, Pengfei Jiang, Kenneth Yin Zhang, Shujuan Liu, Tianshe Yang, Qiang Zhao*, Lijuan Yang, Wen Lv, Qi Yu, Wei Huang*, Multifunctional phosphorescent conjugated polymer dots for hypoxia imaging and photodynamic therapy of cancer cells efficient near-infrared bioimaging[J]. Adv. Sci. 2016, 3(2): 1500155. IF: 17.521, SCI一区

(6) Lingfeng Zhao, Can Zhao, Jiasheng Zhou, Haiwei Ji, Yuling Qin, Guo Li*, Li Wu*, Xiaobo Zhou*, Conjugated polymer-based luminescent probes for ratiometric detection of biomolecules[J]. J. Mater. Chem. B, 2022, 10, 7309-7327. （通讯作者）IF: 7.571, SCI二区

(7) Guo Li, Qi Wang, Jinxia Liu, Mingmin Wu, Haiwei Ji, Yuling Qin*, Xiaobo Zhou*, Li Wu*, Innovative strategies for enhanced tumor photodynamic therapy[J]. Journal of Materials Chemistry B, 2021, 9, 7347-7370. （通讯作者）IF: 7.571, SCI二区

(8) Jinxia Liu, Xiaodi Liu, Luxia Yang, Aiting Cai, Xiaobo Zhou*, Chu Zhou, Guo Li, Qi Wang, Mingmin Wu, Li Wu, Haiwei Ji*, Yuling Qin*. A highly sensitive electrochemical cytosensor based on a triple signal amplification strategy using both nanozyme and DNAzyme[J]. J. Mater. Chem. B, 2022, 10, 700-706. （通讯作者）IF: 7.571, SCI二区

(9) Siyi Yu, Ziqiang Tian, Dongpeng Yang*, Xiaobo Zhou*, Dekun Ma, Shaoming Huang*, Refractive-index-matching-based encryption of photonic crystal prints with multistage and reconfigurable information[J]. Adv. Mater. Interfaces 2021, 8, 2100789.（通讯作者）IF: 6.389, SCI二区

(10) Luxia Yang^#, Xiaobo Zhou^#, Ke Zhang, Jinxia Liu*, Lingfeng Zhao, Aiting Cai, Xinyuan Zhao, Li Wu*, Yuling Qin*, Electrochemiluminescent/Electrochemical ratiometric biosensor for extremely specific and ultrasensitive detection of circulating tumor DNA. Sensor Actuat. B-Chem. 2023, 382, 133490. (共同一作)  IF: 9.221, SCI一区

(11) Rui Chen^#, Xiaobo Zhou^#, Yong Wu, Qingyun Liu, Qian Liu, Jinhua Huang,*,Fuyou Li*.NIR-II emissive lateral flow immunoassay for accurate determination of tumor marker in hemolysis[J]. Sensor Actuat. B-Chem. 2021, 328: 129050. (共同一作)  IF: 9.221, SCI一区

(12) Qiyu Liu^#, Xiaobo Zhou^#, Wei Feng, Tao Pu, Xiaoping Li, Fuyou Li, Yu Kang, Xiaoyan Zhang*, Congjian Xu*, Gonadotropin-releasing hormone receptor-targeted near-infrared fluorescence probe for specific recognition and localization of peritoneal metastases of ovarian cancer[J]. Front. Oncol. 2020, 10: 266. （共同一作）IF: 6.224, SCI二区

(13) Xianmei Zou^#, Xiaobo Zhou^#, Cong Cao, Wenyi Lu, Wei Yuan, Qinyun Liu, Wei Feng*, Fuyou Li*, Dye-sensitized upconversion nanocomposites for ratiometric semi-quantitative detection of hypochlorite in vivo[J]. Nanoscale 2019, 11(5): 2959-2965.（共同一作）IF: 8.307, SCI二区

(14) Qiang Zhao*, Xiaobo Zhou, Tianye Cao, Kenneth Yin Zhang, Lijuan Yang, Shujuan Liu, Hua Liang, Huiran Yang, Fuyou Li*, Wei Huang*, Fluorescent/phosphorescent dual-emissive conjugated polymer dots for hypoxia bioimaging[J]. Chem. Sci. 2015, 6(3):1825-1831. IF: 9.969, SCI一区

(15) Cong Cao, Xiaobo Zhou, Meng Xue, Chunmiao Han, Wei Feng*, Fuyou Li*, Dual Near-Infrared emissive luminescent nanoprobe for ratiometric luminescent monitoring of ClO- in living organisms[J]. ACS Appl. Mater. Interfaces 2019, 11(17): 15298-15305. IF: 10.383, SCI一区

(16) Yingjie Chai, Xiaobo Zhou, Xinyu Chen, Chenqing Wen, Jiaming Ke, Wei Feng*, Fuyou Li* Influence on the apparent luminescent lifetime of rare-earth upconversion nanoparticles by quenching the sensitizer's excited state for hypochlorous acid detection and bioimaging[J]. ACS Appl. Mater. Interfaces 2022, 14, 12, 14004-14011. IF: 10.383, SCI一区

(17) Yawei Liu^#, Yuyang Gu^#, Wei Yuan, Xiaobo Zhou, Xiaochen Qiu, Mengya Kong, Qingbing Wang, Wei Feng, Fuyou Li*, Quantitative mapping of liver hypoxia in living mice using time-resolved wide-field phosphorescence lifetime imaging[J]. Adv. Sci. 2020, 1902929.  IF: 17.521, SCI一区

(18) Wei Wang^#, Qinglai Yang^#, Yahui Du^#, Xiaobo Zhou, Xiaochen Du, Qiuyue Wu, Liyuan Lin,

Yanling Song, Fuyou Li, Chaoyong Yang*, Weihong Tan*, Metabolic labeling of peptidoglycan with NIR-II dye enables in vivo imaging of gut microbiota[J]. Angew. Chem. Int. Ed. 2019, 59: 2628-2633. IF: 16.823, SCI一区

(19) Shengming Cheng, Bin Shen, Wei Yuan, Xiaobo Zhou, Qingyun Liu, Mengya Kong, Yibing Shi, Pengyuan Yang, Wei Feng*, Fuyou Li*, Time-gated ratiometric detection with the same working wavelength to minimize the interferences from photon attenuation for accurate in vivo detection[J]. ACS Cent. Sci. 2019, 5(2): 299-307. IF: 18.782, SCI一区

(20) Haiwei Ji, Xiaoxia Kang, Xiaoxiao Yang, Huanhuan Chen, lvyang Zhu, Tianzhi Mao, Yue He, Jinxia Liu, Qi Wang, Xiaobo Zhou, Guo Li, Mingmin Wu, Hui Cong, Li Wu, Yuling Qin, Functionalized graphene-based electrochemical array sensors for the identification of distinct conformational states of Amyloid Beta in Alzheimer's disease. Biosensors and Bioelectronics. 2023, 222, 114927. IF: 12.545, SCI一区

(21) Guo Li, Mingmin Wu, Yongxiao Xu, Qi Wang, Jinxia Liu, Xiaobo Zhou, Haiwei Ji, Qu Tang, Xijuan Gu, Shujuan Liu, Yuling Qin, Li Wu, Qiang Zhao, Recent progress in the development of singlet oxygen carriers for enhanced photodynamic therapy. Coord. Chem. Rev. 2023, 478, 214979. IF: 24.883, SCI一区

(22) Haiwei Ji, Haolu Hu, Qu Tang, Xiaoxia Kang, Xiaodi Liu, Lingfeng Zhao, Rongrong Jing, Mingmin Wu, Guo Li, Xiaobo Zhou, Jinxia Liu, Qi Wang, Hui Cong, Li Wu, Yuling Qin, Precisely controlled and deeply penetrated micro-nano hybrid multifunctional motors with enhanced antibacterial activity against refractory biofilm infections[J]. J. Hazard. Mater. 2022, 436, 129210. IF: 14.224, SCI一区 

(23) Qingqing Bai, Chaojie Yang, Majun Yang, Zhaoqing Pei, Xiaobo Zhou, Jinxia Liu, Haiwei Ji, Guo Li, Mingmin Wu, Yuling Qin, Qi Wang*, and Li Wu*, pH-Dominated selective imaging of lipid droplets and mitochondria via a polarity-reversible ratiometric fluorescent probe[J]. Anal. Chem. 2022, 94(6), 2901-2911. IF: 8.008, SCI一区

(24) Jinxia Liu, Xiaodi Liu, Huanhuan Chen, Luxia Yang, Aiting Cai, Haiwei Ji*, Qi Wang, Xiaobo Zhou, Guo Li, Mingmin Wu, Yuling Qin*, Li Wu* Bifunctional Pdots-based novel ECL nanoprobe with qualitative and quantitative dual signal amplification characteristics for trace cytokine analysis[J]. Anal. Chem. 2022, 94, 19, 7115-7122. IF: 8.008, SCI一区

(25) Rui Chen, Cuiping Ren, Miao Liu, Xiaopeng Ge, Mingsheng Qu, Xiaobo Zhou, Mifang Liang, Yan Liu*, and Fuyou Li*, Early detection of SARS-CoV-2 seroconversion in humans with aggregation-induced near-infrared emission nanoparticle-labeled lateral flow immunoassaye[J]. ACS Nano 2021, 15(5): 8996-9004. IF: 18.027, SCI一区

(26) Qi Wang, Jin Gong, Qingqing Bai, Yuling Qin, Xiaobo Zhou, Mingmin Wu*, Haiwei Ji*, Li Wu*，Hemoglobin Coated Oxygen Storagable Metal-organic Framework as A Promising Artificial Oxygen Carrier[J].  J. Mater. Chem. B, 2021, 9, 4002-4005. IF: 7.571, SCI二区

(27) Shengming Cheng, Qingyun Liu, Xiaobo Zhou, Yuyang Gu, Wei Yuan, Wei Feng*, and Fuyou Li*, Reversible ratiometric probe combined with the time-gated method for accurate in vivo gastrointestinal pH sensing[J]. ACS Appl. Mater. Interfaces 2020, 12(23): 25557-25564. IF: 10.383, SCI一区

(28) Meng Xue, Cong Cao, Ming Xu, Xianmei Zou, Xiaobo Zhou, Yipeng Zhang, Fuyou Li, Tao Yi*, Wei Feng*, Monitoring energy distribution of nonradiative energy transfer and reabsorption process in an upconversion nanoparticle detection system[J]. Journal of Luminescence, 2019, 210, 175-181. IF: 4.171, SCI三区

(29) Meng Xue, Cong Cao, Xiaobo Zhou, Ming Xu, Wei Feng*, Fuyou Li*, Tuning the upconversion efficiency and spectrum of upconversion nanoparticles through surface decorating of an organic dye[J]. Inorg. Chem. 2019, 58(21): 14490-14497. IF: 5.436, SCI二区

(30) Shujuan Liu, Hua Liang, Kenneth Yin Zhang, Qiang Zhao*, Xiaobo Zhou, Wenjuan Xu, Wei Huang*. A multifunctional phosphorescent iridium(III) complex for specific nucleus staining and hypoxia monitoring. Chem. Commun. 2015, 51, 7943-7946. IF: 6.065, SCI二区

主要科研项目 （选填）

（1）国家自然科学基金青年基金，62005132，pH预靶向协同激活发光探针用于精准活体肿瘤检测和术中诊断，2021.01-2023.12，在研，主持；

（2）江苏省高等学校自然科学研究面上项目，20KJB150040，乏氧响应智能聚合物发光探针用于活体肿瘤精准术中诊断，2020.07-2022.06，已结题，主持；

（3）国家自然科学基金面上项目，32171452，基于多色免疫组织化学的肿瘤免疫微环境分析新技术研究，2022.01-2025.12，在研，骨干成员；

（4）江苏省杰出青年基金项目，BK20220060，面向肿瘤精准治疗需求牵引的医学检验新技术研究，2022.07-2025.06，在研，骨干成员

（5）复旦大学聚合物分子工程国家重点实验室开放研究课题，K2020-01，高亮度聚合物量子点的构建及生物成像应用，2020.01-2021.10，已结题，主持；

（6）江苏省“双创博士”资助项目，2020.07-2022.07，已结题，主持；

（7）澳网官方网站人才引进项目（科研启动经费），酶响应比率荧光探针用于卵巢癌检测，2019.10-2022.09，已结题，主持；

讲授课程

《卫生检验与检测技术基础》、《诊断试剂学》、《分子诊断学》、《检验仪器学》

指导研究生情况

指导研究生4名